Play Now <br> <a href="/fantasy/games/football/office-pool-manager/" class="">Football Pick'em</a> <br> Play Now <br> <a href="https://picks.cbssports.com/college-football/pickem" class="">College Football Pick'em</a> <br> <a href="/podcasts/fantasy-football-today-podcast/" class="">Week 6 Recap</a> <br> <a href="/podcasts/nothing-personal-with-david-samson/" class="">Talking the business of sports</a> <br>The No. 4 <a class="Annotation-link" href="https://www.cbssports.com/college-football/teams/CLEM/clemson-tigers/">Clemson Tigers</a> will try to maintain their unbeaten start to the season when they face the <a class="Annotation-link" href="https://www.cbssports.com/college-football/teams/FSU/florida-state-seminoles/">Florida State Seminoles</a> on Saturday night. Clemson has already picked up a pair of wins over ranked teams this season, and the Tigers are coming off a 31-3 victory over <a class="Annotation-link" href="https://www.cbssports.com/college-football/teams/BC/boston-college-eagles/">Boston College</a>. Meanwhile, Florida State is looking to snap a two-game losing streak after falling to <a class="Annotation-link" href="https://www.cbssports.com/college-football/teams/NCST/nc-state-wolfpack/">NC State</a> in a 19-17 thriller last week. <br>Kickoff is set for 7:30 p.m. ET. The Tigers are favored by 3.5-points in the latest Florida State vs. Clemson odds from Caesars Sportsbook, while the over/under is set at 51. Before entering any Clemson vs. Florida State picks, you'll want to <a href="https://www.sportsline.com/insiders/florida-state-vs-clemson-odds-line-spread-proven-model-reveals-college-football-picks-predictions-for-week-7/#ttag=10132022_agg_cbssports_picks_football_ncaa_model_ClemsonFloridaStatecfbauto" target="_blank" rel="noopener">see the college football predictions from the advanced computer model at SportsLine.</a> <br>The SportsLine Projection Model simulates every FBS <a href="/college-football/" data-is-autolink="true">college football</a> game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its <a href="https://www.sportsline.com/college-football/picks/" target="_blank" rel="noopener">top-rated college football picks against the spread</a>. Anyone who has followed it has seen huge returns.<br>Now, the model has set its sights on <a href="https://www.sportsline.com/college-football/game-forecast/NCAAF_20221015_CLEM@FSU/">Florida State vs. Clemson</a>. You can head to SportsLine to <a href="https://www.sportsline.com/insiders/florida-state-vs-clemson-odds-line-spread-proven-model-reveals-college-football-picks-predictions-for-week-7/#ttag=10132022_agg_cbssports_picks_football_ncaa_model_ClemsonFloridaStatecfbauto" target="_blank" rel="noopener">see its picks.</a> Here are several <a href="https://www.sportsline.com/ncaaf/odds"> college football odds</a> for Florida State vs. Clemson:<br>Florida State is on a two-game losing streak, but both losses have come against ranked teams by 10 points or less. The Seminoles held a 17-3 lead over then-No. 14 NC State last week before surrendering 16 consecutive points down the stretch. They will not have to worry about an emotional letdown on Saturday, as this is their biggest game of the season. <br>Tough games are starting to pile up for Clemson, as this is its third road game in four weeks. Florida State quarterback <a class="Annotation-link" href="/college-football/players/2963373/jordan-travis/">Jordan Travis</a> ranks fourth nationally in the FBS in offensive grade, according to Pro Football Focus. The Seminoles have covered the spread in four of their last five games, and they are 9-3 in their last 12 home games against Clemson. <br>Clemson continues to take care of business against ACC teams, beating <a class="Annotation-link" href="https://www.cbssports.com/college-football/teams/WAKE/wake-forest-demon-deacons/">Wake Forest</a>, NC State and Boston College in consecutive games. The Seminoles lost to both Wake Forest and NC State, making this spread look way too small. Clemson was dominant in all facets of the game last week, blowing out Boston College on the road in a 31-3 final. <br>The Tigers lead the conference in takeaways and are No. 26 nationally in scoring defense. They have also scored at least 30 points in every game this season, averaging 39.3 per game. Clemson has won six consecutive meetings between these teams and is on a 10-game winning streak overall dating back to last season. <br>The model has simulated Clemson vs. Florida State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only <a href="https://www.sportsline.com/insiders/florida-state-vs-clemson-odds-line-spread-proven-model-reveals-college-football-picks-predictions-for-week-7/#ttag=10132022_agg_cbssports_picks_football_ncaa_model_ClemsonFloridaStatecfbauto" target="_blank" rel="noopener">see the pick at SportsLine.</a><br><strong>So who wins Florida State vs. Clemson? And which side of the spread hits in well over 60% of simulations? <a href="https://www.sportsline.com/insiders/florida-state-vs-clemson-odds-line-spread-proven-model-reveals-college-football-picks-predictions-for-week-7/#ttag=10132022_agg_cbssports_picks_football_ncaa_model_ClemsonFloridaStatecfbauto" target="_blank" rel="noopener">Visit SportsLine now to see which side of the Clemson vs. Florida State spread you need to jump on Saturday, all from the model that has crushed its college football picks</a>, and find out.</strong><br>© 2004-2022 CBS Interactive. All Rights Reserved.<br>CBS Sports is a registered trademark of CBS Broadcasting Inc. Commissioner.com is a registered trademark of CBS Interactive Inc.<br>Images by Getty Images and US Presswire<br><br><a href="https://www.cbssports.com/college-football/news/clemson-vs-florida-state-odds-line-bets-2022-week-7-college-football-picks-predictions-from-proven-model/">source</a>
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