Football Power Index game picks are based on 20,000 simulations of a team’s season, using a combination of analytics, including scores to date, quality of opponents, and a team’s schedule.
49ers at Falcons
Sun., Oct. 16 | 1 p.m. | Fox
Point spread: 49ers-4
FPI pick: 49ers 51.4%
Score: Falcons 28, 49ers 14
Patriots at Browns
Sun., Oct. 16 | 1 p.m. | CBS
Point spread: Browns -2.5
FPI pick: Browns 76.2%
Score: Patriots 38, Browns 15
Jets at Packers
Sun., Oct. 16 | 1 p.m. | Fox
Point spread: Packers -7.5
FPI pick: Packers 82.5%
Score: Jets 27, Packers 10
Jaguars at Colts
Sun., Oct. 16 | 1 p.m. | CBS
Point spread: Colts -1.5
FPI pick: Jaguars 59.5%
Score: Colts 34, Jaguars 27
Vikings at Dolphins
Sun., Oct. 16 | 1 p.m. | Fox
Point spread: Vikings -3
FPI pick: Vikings 63.7%
Score: Vikings 24, Dolphins 16
Bengals at Saints
Sun., Oct. 16 | 1 p.m. | CBS
Point spread: Bengals -3
FPI pick: Bengals 60.3%
Score: Bengals 30, Saints 26
Ravens at Giants
Sun., Oct. 16 | 1 p.m. | CBS
Point spread: Ravens -5.5
FPI pick: Ravens 62.9%
Score: Giants 24, Ravens 20
Buccaneers at Steelers
Sun., Oct. 16 | 1 p.m. | Fox
Point spread: Buccaneers -9.5
FPI pick: Buccaneers 82.7%
Score: Steelers 20, Buccaneers 18
Panthers at Rams
Sun., Oct. 16 | 4:05 p.m. | Fox
Point spread: Rams -10
FPI pick: Rams 75.8%
Cardinals at Seahawks
Sun., Oct. 16 | 4:05 p.m. | Fox
Point spread: Cardinals -2.5
FPI pick: Cardinals 64.5%
Bills at Chiefs
Sun., Oct. 16 | 4:25 p.m. | CBS
Point spread: Bills -2.5
FPI pick: Chiefs 58.3%
Cowboys at Eagles
Sun., Oct. 16 | 8:20 p.m. | NBC
Point spread: Eagles -6.5
FPI pick: Eagles 75.5%
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